USP grade nicotine refers to nicotine that meets the standards set by the United States Pharmacopeia (USP), a compendium of quality standards for pharmaceutical substances and products. This designation signifies that the nicotine has been produced, processed, and handled according to strict guidelines to ensure consistency, purity, and safety. USP grade nicotine is commonly used in pharmaceuticals, nicotine replacement therapies (NRTs), and other medical applications where high-quality nicotine is required. Users can trust USP grade nicotine to meet stringent standards for purity and safety established by the USP.